Found 78 matching trials
SAFIR02_Lung - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC Patients
PHASE2Open label multicentric randomized phase II trial, using high throughput ge...
Location
Centre Hospitalier Henri Duffau
Study of Selumetinib (MK-5618) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (MK-5618-001)
PHASE1This study will examine the safety, pharmacokinetics, and efficacy of escal...
Location
City of Hope National Medical Center ( Site 0004)
AZD6244 With Cetuximab for Solid Tumors and Colorectal Cancer
PHASE1Background:
\- The experimental cancer treatment drug AZD6244 has been sho...
Location
National Institutes of Health Clinical Center, 9000 Rockville Pike
To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects
PHASE1A study to assess the pharmacokinetics, safety and tolerability of Selumeti...
AZD6244 (ARRY-142886) Solid Oral Dosage Formulation in Participants With Advanced Solid Malignancies
PHASE1The primary purpose of the study is to assess the safety, tolerability and ...
Status
Active Not Recruiting
Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies
PHASE2Background:
\- The current standard of care for advanced lung cancer and c...
Location
National Institutes of Health Clinical Center
Randomised Study to Compare the Efficacy of AZD6244 vs TMZ
PHASE2The primary purpose of this study is to compare the efficacy of AZD6244 (AR...
To Assess the Effects of Single Oral Dose of Selumetinib [AZD6244; ARRY-142886] [Hyd-Sulfate]), on QTc Interval in Healthy Male Volunteers
PHASE1Study to assess the effect of Selumetinib \[AZD6244; ARRY-142886\] \[Hyd-Su...
Selumetinib for NF2-Related Schwannomatosis
PHASE2The goal of this clinical trial is to evaluate the efficacy and safety of t...
Location
Beijing Tiantan Hospital, Capital Medical University
Selumetinib in Combination With Gefitinib in NSCLC Patients
PHASE1This is an open-label, non-randomized, multicenter phase Ib/II study, which...
Location
National Cheng Kung University Hospital